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Biology • Series

Exemplary: Understanding Model Systems in Biology -- Genetic Regulation

Jonathan O

Series Details

Sessions

Public Discussion

This series ended on July 18, 2024. All 1:1 and group chats related to this series are disabled 7 days after the last session.

Series Details

About

Exemplary: Understanding Model Systems in Biology aims to cover extremely fundamental concepts in biology using model systems. The series will uniquely be drop-in and highly accelerated. One concept will be covered over three to four sessions with increasing complexity and difficulty: starting with AP biology level systems and ending with advanced college course-level understanding. Exemplary is excellent for those with existing knowledge in biology and those looking to pursue a career in biology; knowledge gained will give learners advantage up to junior year of college. The curriculum is heavily inspired by high-level college courses.

Exemplary is taught by Jonathan O, a biochemistry researcher with first-author publication and 1,000+ hours of research experience. He scored a 5 on AP biology and AP chemistry his freshman year by self-studying, and has taken two years worth of credits for the Molecular Biology/Biochemistry track at a T30 university. More info can be found in his schoolhouse profile.

✋ ATTENDANCE POLICY

There are no attendance policies. Feel free to skip classes which cover topics that are too difficult, too easy, or which are not interesting to you. However, you should attend at least one class.

Dates

July 14 - July 18

Learners

5 / 10

Total Sessions

4

About the Tutor

I'm a high school senior from Illinois. I work as a biochemistry researcher and have presented my first-author research at undergraduate research symposiums. I specialize in enzymology with a focus on in vitro kinetics assay characterization and serve as my lab's technical advisor on kinetics assays. I scored a 5 on AP biology and AP chemistry self-studying as a freshman, am an AIME qualifer, scored 1550+ SAT, perfect PSAT, and also have two years worth of credits through dual enrollment each for computer science (T10 university) and molecular biology. I enjoy quizbowl (top 10 nationally) and tennis. Here to help with everything STEM.

View Jonathan O's Profile

Upcoming Sessions

0

Past Sessions

4
14
Jul

Session 1

AP Biology

AP biology-level overview of the lac operon and trp operon regulatory systems. Understanding these is sufficient for full points on the AP exam for questions on regulatory systems. We will start with the basics (the central dogma) and move to promoter sequences, the basic transcription complex, and then to the different kinds of regulation (positive, negative, cis, trans, etc.) with the lac operon and the trp repressor protein.
15
Jul

Session 2

Other Topics

This session is sufficient for introductory and intermediate coursework at the college level. It will continue from the first with the trp operon, expanded: attenuation, tRNA exhaustion, RNA secondary structures, and also eukaryotic regulation with the galactose system in yeast & regulation with chromatin remodeling. We will also cover DNA structural modifying effects in the lac operon.
16
Jul

Session 3

Other Topics

This session is sufficient for intermediate college coursework and above. It will cover the lambda phage lysogenic/lytic determination pathway, a key model regulatory system that covers topics like cooperative binding and the concept of selective loops, where a biological system needs to make a binary decision.
17
Jul

Session 4

Other Topics

This session is sufficient for intermediate college coursework and above. It covers the sex-determination pathway in drosophila melanogaster, or the common fruit fly, and features regulation at the RNA-modification level (regulation through alternative splicing).

Public Discussion

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